Abstract Library

#1630 The Positive Expression of PD-L1/PD-1 in Gastroenteropancreatic Neuroendocrine Neoplasias Correlates with Prognosis

Introduction: The incidence of Neuroendocrine Neoplasias (NENs) is increasing and their pathological characteristics, varied between races. However, the epidemiology of GEP-NENs in Chinese patients remains poorly characterized especially for the expression of important immune checkpoint protein PD1 and PD-L1.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author:

Authors: Yinying W, Chuying W,

Keywords: gastroenteropancreatic neuroendocrine neoplasias, PD-L1, PD-1, immunohistochemistry, prognosis,

#1001 Forkheadbox Proteins as Novel Drug Targets in Gastroenteropancreatic Neuroendocrine Tumor Disease: Inhibition of FoxM1 Exerts Antiproliferative Effects in GEP-NEN Cell Lines

Introduction: Forkheadbox proteins (Fox proteins) are transcriptions factors. They are highly conserved key players in a large number of cellular processes. Fox proteins have been described as acting as both tumor suppressors and oncogenes. Most notably, they operate in the context of the majority of cancer-related pathways. Information about the fuunction of these proteins in gastroenteropancreatic neuroendocrine neoplasias is scant.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author: Briest F

Authors: Briest F, Freitag H, Lewens F, Kaemmerer D, Hörsch D,

Keywords: Forkheadbox proteins, signalling network, immunohistochemistry, siRNA, microarray technique,